منابع مشابه
Worker exposure to vinyl chloride and poly(vinyl chloride).
The National Institute for Occupational Safety and Health (NIOSH) in early 1974 began industrial hygiene studies of vinyl chloride exposed workers. Three VC monomer plants, three VC polymerization plants, and seven PVC fabrication plants were surveyed. V polymerization plant workers and workers in one job category in VC monomer plants were exposed to average levels above 1 ppm. The highest aver...
متن کاملVinyl chloride Toxicological overview
Vinyl chloride is readily and rapidly absorbed via inhalation, ingestion and through the skin At room temperature vinyl chloride is a gas, so inhalation is the major route exposure Following absorption, it is distributed through the body, with the highest concentrations found in the liver and kidneys, followed by the lungs and spleen Vinyl chloride is mainly metabolised in the liver int...
متن کاملVinyl Chloride General information
Toxic by all routes of exposure – inhalation, ingestion, skin contact Carcinogenic in humans Inhalation of vinyl chloride causes coughing, wheezing and breathlessness, headache, ataxia, drowsiness and coma Ingestion of vinyl chloride causes nausea, vomiting, diarrhoea, abdominal pain, and haematemesis may occur. Skin contact causes irritation, pain, burns and contact dermatitis. Rapid...
متن کاملMutagenicity studies of vinyl chloride.
Mutagenicity studies in both man and in test organisms clearly demonstrate positive mutagenic activity of vinyl chloride. In terms of the mutagenicity studies using a variety of in vitro procedures covering both eukaryotes and prokaryotes, positive effects were found. Cytogenetic in vivo studies in animals and in humans indicate not only somatic mutations, but also germinal effects with this ch...
متن کاملToxicity of vinyl chloride and poly(vinyl chloride): a critical review.
In 1974, vinyl chloride (VC) was first reported in the open scientific literature to induce angiosarcoma of the liver both in humans and in animals. Additional research has now demonstrated the carcinogenicity of VC to other organs and at lower concentrations. The target organs for VC now clearly include the liver, brain and the lung, and probably the lymphohematopoietic system. The evidence fo...
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ژورنال
عنوان ژورنال: Kobunshi
سال: 1966
ISSN: 0454-1138,2185-9825
DOI: 10.1295/kobunshi.15.847